BDBM26263 Anexate::CHEMBL407::FLUMAZENIL::Ro15-1788::Romazicon::[3H]Ro15-1788::ethyl 12-fluoro-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(14),3,5,10,12-pentaene-5-carboxylate

SMILES CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(F)ccc-21

InChI Key InChIKey=OFBIFZUFASYYRE-UHFFFAOYSA-N

Data  77 KI  9 IC50  1 Kd  3 Other

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26263   

TargetGamma-aminobutyric acid receptor subunit alpha-1 [28-456]/beta-2 [26-512]/gamma-2 [40-467](Homo sapiens (Human))
University of Wisconsin At Madison

LigandPNGBDBM26263(Anexate | CHEMBL407 | FLUMAZENIL | Ro15-1788 | Rom...)
Affinity DataKi:  3.30nM ΔG°:  -11.4kcal/molepH: 7.4 T: 2°CAssay Description:Membrane homogenates were incubated at room temperature with a sub-Kd concentration of radioligand in the absence or presence of seven different conc...More data for this Ligand-Target Pair